Levamisole Hydrochloride: Uses & Adverse Effects.
Levamisole HCl, initially developed for veterinary applications, has now evolved into crucial in human healthcare. It is recognized by its CAS number 16595-80-5 and EINECS number 240-654-6. This compound is a white crystal powder, noted for its potent anti-parasitic effects. It is mostly produced in China, complying to stringent USP/BP/EP standards.
Levamisole HCl is notable for its efficacy against Ascaris lumbricoides and hookworms. It is crucial for both human and veterinary health. However, understanding the possible Cas 16595-80-5 negative effects and its correct use is vital for safe treatment. This guide explores the notable applications, mechanisms, and negative effects of Levamisole HCl. It seeks to provide a thorough reference for medical experts and patients.
Understanding Levamisole HCl?
Levamisole Hydrochloride, frequently known as pure Levamisole HCl, is a crucial medical compound. Its singular chemical structure, C11H12N2S·HCl, positions it as a significant element in pharmaceutical intermediates. Identified by its CAS number, CAS 240-654-6, this compound is distinguished by its high cleanliness level of 99%, guaranteeing both potency and safety.
Produced from China, Levamisole HCl is renowned for its conformance to USP/BP/EP pharmacopeia requirements. These stringent quality tests verify its properties, including identification, dispersibility, cleanliness, and evaluation findings. Such parameters guarantee its effectiveness as an anti-worm agent, crucial for eliminating parasitic worms in both people and pets.
Below is a detailed summary of Levamisole HCl’s essential features:
| Feature | Details |
|---|---|
| Compound Name | Levamisole HCl |
| Chemical Structure | C11H12N2S·HCl |
| Purity | 99% Levamisole HCl |
| Chemical Abstracts Service Number | CAS 240-654-6 |
| Source | China |
| Use | Drug Intermediates |
This stringent quality control ensures that Levamisole HCl stays a dependable choice within the realm of medical intermediates.
Mechanism of Action of Levamisole
Levamisole Hydrochloride shows a sophisticated mode that combines immune modulation and direct anti-worm activity. This dual operation makes it invaluable in both human and veterinary domains.
Immunomodulatory Effects
As an immunomodulator, Levamisole boosts the immune system’s reaction. It activates various immune cells, helping in the care of autoimmune diseases like rheumatoid arthritis. The mode of action here includes boosting T-cell function. This causes better immune surveillance and the elimination of pathogens.
Anti-Worm Properties
Levamisole HCl is celebrated for its powerful anthelmintic effects. Acting as a dewormer, it disturbs the neuromuscular system of parasitic worms. This results in paralysis and death, effectively removing the infestation. As an anti-parasitic agent, Levamisole HCl undergoes stringent quality control. This guarantees its accuracy and effectiveness in removing parasitic worms.
Main Uses of Levamisole Hydrochloride
Levamisole HCl has developed as a multifaceted agent in both human and veterinary domains. Its purposes span from anti-worm treatments to immunomodulatory therapies, affecting a broad variety of medical and veterinary cases.
Human Medicine
In human medicine, Levamisole Hydrochloride is a powerful parasitic remover, addressing parasitic worm infections. It is approved for treating ascariasis and hookworm infections. Moreover, it plays a role in immunotherapy, boosting the immune reaction in various diseases.
Animal Health Uses
For livestock, Levamisole is vital in handling parasitic infections. It ensures the health and productivity of livestock and pets by eradicating harmful parasites. This drug is crucial for cattle, sheep, goats, and household pets, having a important function in their overall health and condition.
Dosage and Application of Levamisole HCl
Levamisole HCl is a adaptable compound used in both human and veterinary health. It’s important to know the appropriate Levamisole HCl dose and use methods for effective therapy and protection.
Advised Quantities
The suggested quantity for administering Levamisole is between 1.5 to 2.5 mg/kg of body weight. This guarantees the compound is effective and risk-free, minimizing the risk of negative effects. Quantity varies with patient age, weight, and the condition being treated.
Ways of Use
Levamisole HCl use can be done through various methods, based on the patient or animal’s needs. Typical forms consist of:
- Tablets
- Injectable solutions
- Topical applications (less common)
Usage Recommendations
When using Levamisole, it’s crucial to follow the dose guidelines. Here are some usage recommendations:
- Measure and provide the precise Levamisole dosage as a medical expert suggests.
- Know the different needs of species for correct Levamisole administration in veterinary settings.
- Consult a veterinarian or doctor to change dosages according to patient reactions and side effects.
Below is a short table detailing the advised quantities for various species:
| Species | Dosage | Type |
|---|---|---|
| People | 2.5 mg/kg | Tablet |
| Bovine | 1.5-2.5 mg/kg | Injectable |
| Ovines | 1.5-2.0 mg/kg | Oral |
Appropriate Levamisole use confirms treatment efficacy and reduces adverse reactions. This causes better effects for individuals and animals alike.
Likely Reactions of Levamisole
Levamisole Hydrochloride is generally celebrated for its efficacy. However, it’s vital to accept potential negative effects. This confirms they are promptly identified and handled.
Frequent Side Effects
Gastrointestinal symptoms are among the most frequent CAS 136-47-0 negative effects. These consist of nausea, vomiting, and abdominal pain. Some individuals might also experience headaches. These symptoms, although generally mild, can be quite bothersome. They might result in stopping the treatment or adjusting the quantity.
Critical Side Effects
Levamisole overdose can result in critical health issues. A major problem is agranulocytosis, which significantly reduces white blood cell counts. This makes people very prone to infections. Other critical negative effects consist of vasculitis, which is inflammation of the blood vessels, and severe skin reactions such as rashes.
Healthcare professionals recommend careful supervision for any adverse reactions to Levamisole. Regular visits and blood tests are recommended to minimize serious complications. This vigilant strategy is crucial to balance the care’s benefits against its risks.
Cautions and Advisories
When thinking about the application of Levamisole, it is critical to follow specific cautions to confirm health and safety. People should refrain from Levamisole if they have a documented hypersensitivity to the drug or preexisting ailments such as liver or kidney disease. These are important Levamisole cautions to lower any negative effects.
Expecting or breastfeeding women, as well as those with compromised immune systems, should talk to a medical expert before starting therapy with Levamisole HCl. This action is important for ensuring high levels of Levamisole safety. Additionally, regular blood tests could be necessary to monitor the compound’s effects on the body, which highlights the importance of remaining cautious.
It is also important to adhere to rigorous storage and handling protocols to maintain the compound’s integrity and efficacy. Proper storage conditions are keeping Levamisole HCl in a chilly, arid place away from direct sunlight. These Levamisole alerts are not to be ignored, as improper handling can lead to diminished effectiveness and possible risks.
| Issue | Action |
|---|---|
| Known hypersensitivity | Avoid usage |
| Liver or kidney conditions | Consult healthcare provider |
| Pregnant or breastfeeding | Consult healthcare provider |
| Compromised immune system | Talk to doctor |
| Routine blood tests | Monitor drug effects |
| Keeping | Cool, dry place away from sunlight |
Levamisole HCl in Animal Healthcare
Levamisole HCl is crucial in veterinary care, addressing parasitic diseases in livestock and pets. It enhances animal health and productivity when used correctly.
Animal Uses
In livestock care, Levamisole Hydrochloride is crucial to fighting parasitic infections in animals. As a strong Levamisole anti-worm agent, it enhances health and productivity in cattle, sheep, and pigs. The dosage must be accurately calculated, based on the animal’s species and weight for best results and safety.
Pet Safety
Guaranteeing pets’ safety with Levamisole HCl for pets is essential. Veterinarians emphasize the importance of accurate diagnosis and treatment plans to prevent negative effects. Thorough assessments assist determine if Levamisole for pets is suitable for each pet, guaranteeing their health and well-being.
Keeping and Managing of Levamisole
Preserving Levamisole appropriately is crucial for its potency and safety. Levamisole Hydrochloride should be kept in airtight containers. It should be stored in a cold, dry spot, away from light, moisture, and pests. This guarantees the medication stays strong and risk-free for longer.
Here are some tips for managing Levamisole to preserve its pharmaceutical quality:
| Storing Conditions | Advice |
|---|---|
| Storage Box | Airtight, sealed |
| Heat Level | Normal temperature (20-25°C) |
| Environment | Cold, moisture-free, and out of sunlight |
| Humidity Management | Moisture absorbers suggested |
| Pest Prevention | Store in a pest-free area |
| Expiration Date | Follow expiry date |
By adhering to these guidelines, Levamisole HCl remains within the purity range required by pharmaceutical standards. Proper storage and handling of Levamisole HCl preserves its effectiveness for future use.
Comparisons with Other Therapies
When comparing Levamisole HCl with other medications, it’s crucial to look at their unique therapeutic profiles and applications.
Comparing Levamisole and Tetracaine
Levamisole HCl and Tetracaine have completely different therapeutic uses. Tetracaine is a powerful local anesthetic, used to reduce sensation during medical procedures. It acts by blocking nerve signals, making it suitable for surgeries and minor medical interventions.
Levamisole, on the other hand, is an immune enhancer and anti-worm agent. Its ability to modulate the immune system and eradicate parasitic infections differentiates it from Tetracaine. Unlike Tetracaine, Levamisole is not used for anesthesia. Instead, it is crucial in managing autoimmune diseases and parasitic infections.
Levamisole vs Procaine
Levamisole HCl and Procaine also have distinct therapeutic purposes. Procaine, like Local anesthetic, is a local anesthetic used to cause temporary numbness in specific areas for procedures such as dental work and minor surgeries. It achieves this by blocking sodium channels, stopping pain signals from reaching the brain.
Levamisole HCl, however, is aimed at boosting the body’s immune function and targeting parasitic worms. This is a big difference from Procaine’s numbing effect. Levamisole HCl does not act as a local anesthetic but supports the body’s defense mechanisms and addresses infections from parasitic organisms.
Below is a comprehensive differentiation of Levamisole HCl with Tetracaine and Procaine:
| Parameter | Levamisole HCl | Tetracaine | Procaine |
|---|---|---|---|
| Primary Use | Immune booster and parasitic remover | Numbing agent | Pain reliever |
| Mode of Operation | Boosts Immune System, Eliminates Parasitic Infections | Inhibits pain signals | Stops sodium channels |
| Purpose | Addresses autoimmune issues and parasitic infections | Used in Surgeries and Minor Medical Procedures | Employed in dental tasks and small operations |
Grasping the distinctions between Levamisole, Tetracaine, and Procaine aids medical professionals in selecting the most fit care for their patients. This ensures safer and more successful medical outcomes.
Summary: Advantages and Cons of Levamisole HCl
Levamisole Hydrochloride is notable as a vital medical compound in human and animal care. It’s known for its powerful anthelmintic properties, effectively addressing parasitic infections. Additionally, it improves the immune system in some clinical settings, making it a popular choice for doctors and vets.
However, Levamisole is not without its cons. The list of Levamisole risks contains negative effects that range from mild to severe. While minor issues like nausea and dizziness are tolerable, severe blood disorders require close attention. Thus, a comprehensive Levamisole HCl review must account for both its advantages and its risks.
For those considering Levamisole HCl, a deep understanding is essential. Health experts and pet owners must meticulously evaluate the pros of Levamisole against the possible risks. Confirming responsible use, correct dosing, and vigilant monitoring is vital. This well-rounded method is crucial for risk-free and efficiently using Levamisole.
